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Stephanie H Geller

Stephanie H Geller

Molecular Biologist and Biomedical Engineer

Madison, WI
+1 (507) 317-5133

Background


About

About

Ph.D.-trained molecular biologist and biomedical engineer with 7+ years of experience in fungal pathogenesis and synthetic biology. Skilled leader with a strong record of mentoring, project management, and lab operations. Experienced communicator with 3 peer-reviewed publications (2 first/co-first author), 8 conference presentations, and multiple research awards. Experienced in bridging scientific innovation with organizational goals through collaboration and clear communication.

Work Experience

Work Experience

  • Scientist, Molecular Biology, Xylome Corporation

    Jan, 2024 - Sep, 20251 year 8 months

    Led molecular biology projects to engineer yeast strains for higher oil yield and improved fermentation workflows. Mentored junior scientists, communicated technical progress to clients and stakeholders, and coordinated R&D activities with product goals.

    • Designed and engineered yeast strains for high-efficiency oil production to improve fermentation processes.

    • Mentored junior scientists and staff; provided technical guidance and fostered collaborative problem-solving.

    • Presented research and project updates to clients, shareholders, and government agencies.

    • Aligned R&D goals with business objectives to bridge scientific and commercial needs.

  • Postdoctoral Researcher, University of Wisconsin-Madison, Laboratory of Dr. Megan McClean

    May, 2023 - Jul, 20232 months

    Focused on RNA-seq data analysis to identify candidate genes for fungal pathogenesis and biofilm studies. Mentored a new graduate student and supported experimental design for follow-up projects.

    • Mentored a new graduate student to establish independent projects based on prior RNA-seq work.

    • Collaboratively analyzed RNA-seq data to identify key genes for follow-up studies.

  • Graduate Research Assistant, University of Wisconsin-Madison, Laboratory of Dr. Megan McClean

    Sep, 2017 - May, 20235 years 8 months

    Conducted dissertation research on Candida albicans biofilm development and dispersion using microfluidics, RNA-seq, and optogenetic tools. Designed experiments, utilized analysis pipelines (MATLAB/Python), and mentored undergraduate researchers.

    • Co-developed under-oil microfluidics for screening large mutant libraries across the C. albicans lifecycle, focusing on dispersion.

    • Screened 165 transcription factor mutants for dispersion phenotypes using 96-well and microfluidic assays.

    • Performed RNA-seq and advanced analyses to characterize regulation of a transcriptional regulator in fungal biofilm development.

    • Adapted optogenetic tools (CRY2/CIB1) from S. cerevisiae to C. albicans, enabling light-controlled transcription.

    • Utilized analysis pipelines (MATLAB, Python) for robust, systematic data analysis.

  • Bioprocess R&D Intern, IFF / Danisco US

    Jan, 2022 - Mar, 20222 months

    Developed and validated protocols for BactoBox and Lyotherm 3 to support probiotics and dairy enzyme research. Trained staff on equipment use and presented testing results to Process R&D.

    • Developed protocols for BactoBox and Lyotherm 3 to support probiotics and dairy enzyme research.

    • Trained team members on BactoBox operation and presented equipment testing results to Process R&D.

  • Research Intern, University of Wisconsin-Madison, Laboratory of Dr. Megan McClean

    Jun, 2015 - Aug, 20172 years 2 months

    Built and validated optogenetic constructs in S. cerevisiae, established laboratory workflows for C. albicans, and led undergraduate teams on microfluidics and lifecycle experiments.

    • Developed optogenetic tools for transcriptional control in S. cerevisiae using homologous recombination, Gibson, and Golden Gate assembly.

    • Established C. albicans as a lab organism including growth, storage, transformation, and experimental parameters.

    • Led undergraduate teams to study C. albicans physiology; developed microfluidics for lifecycle studies (dispersion).

  • Undergraduate Research Lab Assistant, University of Minnesota, Duluth, Laboratory of Dr. Jennifer Liang

    Jun, 2014 - May, 201511 months

    Supported zebrafish developmental biology projects with microscopy and in situ hybridization, assisted with mutant screening, and maintained animal care routines.

    • Assisted with data collection and mutant embryo identification via in situ hybridization and brightfield microscopy.

    • Maintained Danio rerio (zebrafish) adults and embryos, including feeding schedules and tank upkeep.

Projects Experience

Projects Experience

  • Unraveling Candida albicans dispersion by screening transcription factor mutants, Midwest Microbial Pathogenesis Conference

    Oct, 2022 - Oct, 20221 day

  • Shining light on the process of dispersion in Candida albicans, Central US Synthetic Biology Workshop

    Oct, 2022 - Oct, 20221 day

  • Microfluidic and Optogenetic Tools for Studying Biofilm Development and Dispersion in Candida albicans, Candida and Candidiasis Conference

    Mar, 2021 - Mar, 20211 day

  • YOTK: Tools to Tune Intracellular Protein Concentration, 30th Fungal Genetics Conference

    Mar, 2019 - Mar, 20191 day

Skills

Skills

  • Molecular Biology

    CRISPR

    DNA transformations (S. cerevisiae, E. coli, C. albicans)

    Gene expression analysis

    Gibson Assembly

    Golden Gate Assembly

    Nucleic acid isolation

    PCR

    RNA isolation

    RNA sequencing

    Site-directed mutagenesis

    Western blot

    Yeast mating

    qRT-PCR

    Gel electrophoresis

  • Imaging

    Brightfield microscopy

    Fluorescence microscopy

    Confocal microscopy

  • Data Analysis

    Excel

    MATLAB

    Python

  • Laboratory & Platforms

    Optogenetics

    Microfluidics

    Flow cytometry

    Liquid handling automation

    Cell culture and maintenance

    Metabolic assays

    Biofilm growth

    SOP development

    ELN

    LIMS

  • Interpersonal

    Problem solving

    Mentoring

    Independent and team-oriented

    Project management

    Multitasking

Education

Education

  • Cellular and Molecular Biology, Ph.D., University of Wisconsin-Madison

    Jan, 2017 - Jan, 2023

    Department of Biomedical Engineering affiliation

  • Biology (Psychology minor), B.S., University of Minnesota, Duluth

    Jan, 2012 - Jan, 2015

    Department of Biology

  • Molecular Mycology, Certificate, Marine Biological Laboratory

    Jan, 2019 - Jan, 2019

Awards

Awards

  • Session Moderator, UW-Madison Genomics Retreat

    Awarded on: Jan 01, 2023

  • Invited Speaker, Candida & Candidiasis Conference

    Awarded on: Jan 01, 2020

  • Candida and Candidiasis Access Bursary Funds

    Awarded on: Jan 01, 2020

  • Student Research Travel Grant, University of Wisconsin–Madison

    Awarded on: Jan 01, 2020

  • Invited Speaker, 30th Fungal Genetics Conference

    Awarded on: Jan 01, 2019

  • Student Research Travel Grant, University of Wisconsin-Madison

    Awarded on: Jan 01, 2019

  • CMB Travel Award

    Awarded on: Jan 01, 2019

  • Magna Cum Laude Graduate, University of Minnesota, Duluth

    Awarded on: Jan 01, 2015

Publications

Publications

Interests

Interests

  • Horseback riding

  • Hiking

  • Kayaking

  • Board games

  • Traveling